Malignant salivary gland tumours: Can fast neutron therapy results point the way to carbon ion therapy?
نویسندگان
چکیده
منابع مشابه
Malignant Salivary Gland Tumours
PCNA (proliferating cell nuclear antigen) immunoreactivity is high in malignancy. (Also ki67 antibodies) and thus provides a useful diagnostic tool. Ki67 has prognostic significance in Adenoid Cystic Carcinoma. Bcl 2 and apoptotic index are good prognostic markers. Bax is proapoptotic (in salivary neoplasms there is decreased Bcl 2 and increased Bax leading to increased apoptosis ) Cytokeratin ...
متن کاملRaster-scanned carbon ion therapy for malignant salivary gland tumors: acute toxicity and initial treatment response
BACKGROUND AND PURPOSE To investigate toxicity and efficacy in high-risk malignant salivary gland tumors (MSGT) of the head and neck. Local control in R2-resected adenoid cystic carcinoma was already improved with a combination of IMRT and carbon ion boost at only mild side-effects, hence this treatment was also offered to patients with MSGT and microscopic residual disease (R1) or perineural s...
متن کاملMalignant Salivary Gland Tumours of the Nasal Sinuses and Exophthalmos.
TUMOURS of the ethmoid, maxillary, frontal, and sphenoid air sinuses usually manifest themselves by proptosis. They may take the form of osteoma, chondroma, osteoclastoma, fibroma, myxoma, angioma, psammoma, endothelioma, carcinoma, or sarcoma (Duke-Elder, 1952). The mucous membrane of these sinuses contains not only epithelial and fibro-adenoid layers but also a layer of mucous and serous glan...
متن کاملSalivary gland tumours.
Salivary gland tumours are a relatively rare and morphologically diverse group of lesions. Although most clinicians and pathologists will have encountered the more common benign neoplasms, few have experience of the full range of salivary cancers, which are best managed in specialist centres. This review considers some current areas of difficulty and controversy in the diagnosis and management ...
متن کاملFast neutron therapy for malignant astrocytomas. A review.
The treatment of supratentorial malignant gliomas has continued to be a major problem for neurosurgeons and oncologists. Post-operative conventional radiotherapy is known to prolong survival and to enhance the quality of life. Local persistence of tumor kills the majority of patients. Fast neutron irradiation is being utilized to treat malignant gliomas based on its reputed radiobiological adva...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2013
ISSN: 0167-8140
DOI: 10.1016/j.radonc.2013.08.013